Every year more than 2 million people die from occupational accidents or work-related diseases. By conservative estimates, there are 270 million occupational accidents and 160 million cases of occupational disease. The safety of work varies enormously between countries, economic sectors and social groups. Deaths and injuries take a particularly heavy toll in developing nations, where large numbers of people are engaged in hazardous activities such as agriculture, construction, logging, fishing and mining. Throughout the world, the poorest and least protected – often women, children and migrants – are among the most affected. The ILO places special importance on developing and applying a preventative safety and health culture in workplaces worldwide. In 2003, the ILO began to observe World Day stressing the prevention of illness and accidents at work on every 28 April, capitalizing on its traditional strengths of tripartism and social dialogue. 28 April is also a day the world's trade union movement has long associated with commemorating victims of occupational accidents and disease.